systemic

S1Y4S1T1E1M3I1C3
UK/sɪˈstɛm.ɪk/UK/sɪˈstiː.mɪk/Australia/sɪˈstem.ɪk/New Zealand/səˈstem.ək/

adjective

Embedded within and spread throughout and affecting a whole system, group, body, economy, market, or society.

CommonScrabble 15

Meanings

adjectivesystemic (not comparable)
  1. not comparableEmbedded within and spread throughout and affecting a whole system, group, body, economy, market, or society.

    We can learn from the incidents found it the project database - looking at them and understanding what happened and what might have been done differently. We can see past errors, including systemic issues that required attention at managerial levels.

    2022 August 10, Dr Mike Esbester, “New understandings from old incidents”, in RAIL, number 963, page 59
  2. not comparablemedicinePertaining to an entire organism.

    Iberdomide, a cereblon modulator promoting degradation of the transcription factors Ikaros and Aiolos, which affect leukocyte development and autoimmunity, is being evaluated for the treatment of systemic lupus erythematosus (SLE).

    2022 March 17, Joan T. Merrill, Victoria P. Werth, Richard Furie et al., “Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus”, in The New England Journal of Medicine, volume 386, number 11, →DOI, page 1034

    Synonyms: holistic

Synonyms & antonyms

adjectivePertaining to an entire organism.

Similar
Opposite

antonym(s) of “widespread, prevalent”

Opposite

More synonyms by meaning

adjectiveaffecting an entire system

Similar

Synonym sets from Open English WordNet, CC BY 4.0.

Origin

Translations

Arabic نِظَامِيّ
  • نِظَامِيّ (niẓāmiyy)relating to a system
Bulgarian систе́мен
  • систе́мен (sistémen)relating to a system
Catalan sistèmic, sistèmic
  • sistèmicrelating to a system
  • sistèmicpertaining to an entire organism
Czech systémový
  • systémovýrelating to a system
Danish systemisk
  • systemiskrelating to a system
Finnish systeeminen, systeeminen
  • systeeminenrelating to a system
  • systeeminenpertaining to an entire organism
French systémique, systémique
  • systémiquerelating to a system
  • systémiquepertaining to an entire organism
German systemisch, System-
  • systemischrelating to a system
  • System-relating to a system
Hungarian rendszerszerű, rendszerszintű
  • rendszerszerűrelating to a system
  • rendszerszintűpertaining to an entire organism
  • általánospertaining to an entire organism
  • átfogópertaining to an entire organism
Indonesian sistemis, sistemis
  • sistemisrelating to a system
  • sistemispertaining to an entire organism
Italian sistemico
  • sistemicopertaining to an entire organism
Malay sistemik, sistemik
  • sistemikrelating to a system
  • sistemikpertaining to an entire organism
Polish systemowy, ogólnoustrojowy
  • systemowyrelating to a system
  • ogólnoustrojowypertaining to an entire organism
Portuguese sistêmico
  • sistêmicopertaining to an entire organism
Russian систе́мный
  • систе́мный (sistémnyj)relating to a system
Slovak systémový
  • systémovýrelating to a system
Spanish sistémico, sistémico
  • sistémicorelating to a system
  • sistémicopertaining to an entire organism
Ukrainian систе́мний
  • систе́мний (systémnyj)relating to a system

Rhymes & wordplay

Rhymes with systemic

All rhymes →
Cite this entry
APA

systemic. (n.d.). In WatkinsX Dictionary. Retrieved November 2, 2026, from https://dictionary.watkinsx.com/word/systemic

MLA

“systemic.” WatkinsX Dictionary, https://dictionary.watkinsx.com/word/systemic. Accessed November 2, 2026.

Chicago

WatkinsX Dictionary, s.v. “systemic,” accessed November 2, 2026, https://dictionary.watkinsx.com/word/systemic.

Source: systemic on Wiktionary, CC BY-SA 4.0.